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Symbol Name ID |
Dusp1
dual specificity phosphatase 1 MGI:105120 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | immune system phenotype |
increased mast cell degranulation |
increased granulocyte number |
increased circulating interferon-gamma level |
increased circulating interleukin-10 level |
increased circulating interleukin-6 level |
increased circulating tumor necrosis factor level |
abnormal chemokine level |
abnormal interleukin level |
increased susceptibility to type I hypersensitivity reaction |
abnormal cytokine secretion |
abnormal chemokine secretion |
increased interleukin-1 beta secretion |
increased interleukin-6 secretion |
increased tumor necrosis factor secretion |
increased susceptibility to induced arthritis |
increased susceptibility to endotoxin shock |
lung inflammation |
abnormal innate immunity |
increased susceptibility to bacterial infection |
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| Availability | Mouse Genotype | ||||||||||||||||||||
| Dusp1tm1Brv/Dusp1tm1Brv | * | ||||||||||||||||||||
| Dusp1tm1Lex/Dusp1tm1Lex | |||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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